When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma.

Abstract

BACKGROUND:

Pheochromocytoma is known for its instantaneous presentation, especially in the younger population. Hemodynamic instability may be the cause of severe complications and impede patients' ability to undergo surgical treatment. These tumours are surgically difficult to treat due to the risk of catecholamine release during their manipulations, and when they are large, the tumour size represents an additional challenge. In our report, cardiogenic shock developed due to increases in systemic vascular resistance, and the lesion's size induced surgeons to perform open surgery.

CASE PRESENTATION:

A 46-year-old female patient was admitted to our intensive care unit with hypertension and later cardiogenic shock. Systolic dysfunction was noted, along with severely increased systemic vascular resistance. A CT scan showed a left-sided 8.5 cm adrenal mass, which was confirmed as pheochromocytoma using meta-iodobenzylguanidine scintigraphy. Anaesthesiologists and the surgical team planned an effective strategy of treatment. Given the lesion's size and its apparent invasion of the neighbouring organs, open adrenalectomy (after prolonged hemodynamic stabilisation) was considered safer. The surgery was successful, and the patient remains free from disease two years after the initial event.

CONCLUSIONS:

Large pheochromocytoma can be safely and effectively treated with open surgery by experienced hands but only by seeking to reach hemodynamic stabilisation and minimising the release of catecholamine before and during surgery.

• Authors: Raffaele Baio, Tommaso Pagano, Giovanni Molisso, Umberto Di Mauro, Olivier Intilla, Francesco Albano, Fulvio Scarpato, Stefania Giacometti, Roberto Sanseverino
• Journal: Diseases (Basel, Switzerland) (Diseases) Vol. 10 Issue 2 (May 17 2022) ISSN: 2079-9721 [Print] Switzerland
• PMID: 35645250 (Publication Type: Journal Article)