Visual and endocrine outcome following surgery for pituitary adenoma in a tertiary hospital, North Central Nigeria.

Abstract

BACKGROUND:

It becomes expedient in our emerging practice to evaluate the outcome of pituitary surgery.

AIMS AND OBJECTIVES:

Outcome following Surgery for Pituitary Adenoma in a Resource Challenged Tertiary Hospital.

METHODS:

Retrospective review of cases of surgery for pituitary adenomas (Jan 2013-Dec 2017).

RESULTS:

Total 28 out of 57 cases (49%) had surgery. M: F 3:1. Mean age of 44 years (range 21-72 years). 23/28(82%) were referred from eye clinics. Commonest presentation was visual impairment (100%) and Hormone dysfunction. Mean time to presentation was 29 months. Commonest pre-op diagnosis was non-functional adenoma 24/29 (85.7%). Commonest surgical approach was transsphenoidal surgery 20/28 (70.1%). At 12 months, visual improvement was recorded in 39.2%. Some improvement in hormone status was recorded but prolactinemia persisted in 7.1% while GH secreting persisted in 3.5%. Residual/recurrent tumor at 12 months scan was recorded in 59.2%.

CONCLUSION:

A marginal improvement in vision was observed but hypocortisolism and low thyroid hormones were restored to normalcy at 12 months. However, Growth Hormones and Prolactin remained mostly unchanged at 12 months.

• Authors: Ugwuanyi Charles, Anigbo Anthony, Nwaribe Emeka, Okpata Cyril, Ayogu Obinna, Salawu Morayo, Ekumankama Obasi, Jamgbadi Shola, Paul Jibril, Arua Chinedu, Arewa Folusho
• Journal: British journal of neurosurgery (Br J Neurosurg) Pg. 1-4 (Apr 28 2022) ISSN: 1360-046X [Electronic] England
• PMID: 35481405 (Publication Type: Journal Article)