Demographic characteristics, risk factors, and clinical variables associated with
gonorrhea and chlamydial
infection in women being treated in emergency departments (EDs) in the United States are incompletely characterized. We used univariable and multivariable regression analyses on 17,411 encounters from women 18 years and older who presented to EDs in northeast Ohio and were tested for
gonorrhea or chlamydial
infection. There were 1,360 women (7.8%) who had Chlamydia trachomatis
infection and 510 (2.9%) who had
Neisseria gonorrhoeae infection. Those infected with C. trachomatis or N. gonorrhoeae were younger (23.8 vs. 29.2 years), unmarried (97.7% vs. 90.1%), Black (93.3% vs. 88.0%), infected with Trichomonas vaginalis (39.9% vs. 27.2%), diagnosed with
urinary tract infection (15.7% vs. 10.6%), and treated for
gonorrhea and chlamydial
infection during the ED visit (31.6% vs. 17.4%) (all ps < .001). Women infected with C. trachomatis or N. gonorrhoeae had more urine white blood cells (WBCs) (23.9 vs. 16.4 cells per high-power field [HPF]) and
leukocyte esterase (1.2+ vs. 0.8+) on urinalysis. They had more WBCs (18.5 vs. 12.4 cells/HPF) and odds of having T. vaginalis
infection (12.8% vs. 8.2%) on vaginal wet preparation (all ps < .001). Women infected with C. trachomatis were more likely to be younger and not Black; they were less likely to be treated for
gonorrhea and chlamydial
infection in the ED and to have lower levels of urine WBCs,
leukocyte esterase, and blood than those infected with N gonorrhoeae (all ps ≤ .05).