Current Status of Metabolic/Bariatric Surgery in Type 1 Diabetes Mellitus: an Updated Systematic Review and Meta-analysis.

Abstract

This systematic review and meta-analysis intend to evaluate the efficacy of metabolic/bariatric surgeries (MBS) in patients with type-1 diabetes mellitus. A systematic literature search and meta-analysis were performed in electronic databases up to July 2021. In total, 27 primary studies comprising 648 subjects were included in this systematic review and meta-analysis. Patients had a mean age of 38.0 ± 7.3 years. Preoperative mean BMI was 42.6 ± 4.7 kg/m2 and 29.4 ± 4.7 kg/m2 after surgery, respectively. Following bariatric surgeries in patients with type 1 diabetes mellitus, insulin (unit/day) decreased by a weighted mean difference (WMD) of - 10.59. Also, insulin (unit/kg/day) decreased by a WMD of - 0.2, and HbA1C decreased by a WMD of - 0.71, showing MBS acceptable and durable effects of bariatric surgical procedures.

• Authors: Mohammad Kermansaravi, Rohollah Valizadeh, Amirhossein Davarpanah Jazi, Shahab Shahabi Shahmiri, Jose Antonio Lopez Martinez, Ali Mousavimaleki, Foolad Eghbali, Amirhossein Aliakbar, Hamed Atarodi, Ebrahim Aghajani, Panagiotis Lainas
• Journal: Obesity surgery (Obes Surg) Vol. 32 Issue 5 Pg. 1726-1733 (05 2022) ISSN: 1708-0428 [Electronic] United States
• PMID: 35211844 (Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
• Copyright: © 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Chemical References

• Insulin

Topics

• Adult
• Bariatric Surgery (methods)
• Diabetes Mellitus, Type 1 (complications, surgery)
• Diabetes Mellitus, Type 2 (surgery)
• Humans
• Insulin
• Middle Aged
• Obesity, Morbid (surgery)