Cutaneous ulceration as a presenting feature of type 1 lepra reaction: A case report.

Abstract

Reactions in leprosy represent sudden shift in the immunological response and are seen in 11-25% of affected patients. It can be seen before, during or after the completion of multidrug therapy (MDT).1 Two types of reactions are recognized; Type 1 reaction (T1R), seen in borderline leprosy, affecting mainly skin and nerves; type 2 reaction (T2R) or erythema nodosum leprosum (ENL), seen in lepromatous leprosy, characterized by systemic features in addition to cutaneous lesions. Trophic ulcers and ulcerating ENL are well known entities while cutaneous ulceration in T1R is extremely rare; we describe an immune-competent woman with cutaneous ulceration as a presenting feature to highlight the need to recognize this entity at the earliest opportunity.

• Authors: Pallavi Hegde, Deepti Jaiswal, Varsha M Shetty, Kanthilatha Pai, Raghavendra Rao
• Journal: Tropical doctor (Trop Doct) Vol. 52 Issue 2 Pg. 354-356 (Apr 2022) ISSN: 1758-1133 [Electronic] England
• PMID: 35006027 (Publication Type: Case Reports, Journal Article)

Chemical References

• Leprostatic Agents

Topics

• Drug Therapy, Combination
• Erythema Nodosum (diagnosis, drug therapy, etiology)
• Female
• Humans
• Leprostatic Agents (therapeutic use)
• Leprosy, Borderline (complications, drug therapy, pathology)
• Leprosy, Lepromatous (complications, diagnosis, drug therapy)
• Skin Ulcer (diagnosis, drug therapy, etiology)