Abstract | INTRODUCTION:
Diabetes mellitus (DM) comprises differential clinical phenotypes ranging from rare monogenic to common polygenic forms, such as type 1 (T1DM), type 2 (T2DM), and gestational diabetes, which are associated with cardiovascular complications. Also, the high- -risk prediabetic state is rising worldwide, suggesting the urgent need for early personalized strategies to prevent and treat a hyperglycemic state. OBJECTIVE: We aim to discuss the advantages and challenges of Network Medicine approaches in clarifying disease-specific molecular pathways, which may open novel ways for repurposing approved drugs to reach diabetes precision medicine and personalized therapy. CONCLUSION:
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Authors | Claudio Napoli, Giuditta Benincasa, Samer Ellahham |
Journal | Current diabetes reviews
(Curr Diabetes Rev)
Vol. 18
Issue 8
Pg. e221221199301
( 2022)
ISSN: 1875-6417 [Electronic] United Arab Emirates |
PMID | 34951369
(Publication Type: Journal Article)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
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Topics |
- Biomarkers
- Diabetes Mellitus, Type 1
(genetics)
- Diabetes Mellitus, Type 2
(drug therapy, genetics)
- Humans
- Phenotype
- Precision Medicine
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