HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

valdecoxib (Bextra)

a COX-2 inhibitor; structure in first source

Also Known As:

Bextra; Pfizer brand of valdecoxib; Pharmacia brand of valdecoxib; SC 65872; SC-65872; 4-(5-methyl-3-phenyl-isoxazol-4-yl)benzenesulfonamide

Networked: 139 relevant articles (44 outcomes, 48 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Experts

1.	Verburg, Kenneth M: 9 articles (02/2006 - 01/2002)
2.	Recker, David P: 9 articles (02/2003 - 01/2002)
3.	Joshi, Girish P: 4 articles (01/2009 - 02/2004)
4.	Rabasseda, X: 4 articles (09/2007 - 01/2003)
5.	Prous, J R: 4 articles (09/2007 - 01/2003)
6.	Brown, Mark T: 4 articles (02/2006 - 08/2004)
7.	Pan, Sharon: 3 articles (01/2009 - 06/2007)
8.	Desjardins, Paul J: 3 articles (01/2005 - 05/2002)
9.	Daniels, Stephen E: 3 articles (01/2005 - 05/2002)
10.	Verburg, K M: 3 articles (09/2004 - 07/2003)

Related Diseases

1.	Pain (Aches) 08/01/2004 - "Pain scores on the mBPI-SF indicated significantly greater pain relief with valdecoxib at each assessment (all, P < or = 0.014 vs placebo). " 08/01/2004 - "No statistically significant differences in patient baseline characteristics were noted between treatment groups, except in response to 1 mBPI-SF question; patients in the valdecoxib group reported significantly greater interference in relations with other people due to pain than did those in the placebo group (P = 0.048). " 01/01/2002 - "Pain intensity levels and patient satisfaction were significantly improved in both valdecoxib groups compared with placebo. " 01/01/2004 - "Pre-emptive administration of valdecoxib 10-80 mg was particularly effective in dental pain. " 09/01/2006 - "Two randomized, double-blind, placebo-controlled studies assessed the analgesic efficacy of valdecoxib in patients with moderate-to-severe pain after bunionectomy. " Order ALL the reference details at left...
2.	Rheumatoid Arthritis 06/01/2007 - "Efficacy and tolerability of valdecoxib in treating the signs and symptoms of severe rheumatoid arthritis: a 12-week, multicenter, randomized, double-blind, placebo-controlled study." 02/15/2003 - "The analgesic efficacy of valdecoxib at a dose of 10 mg once daily in both osteoarthritis and rheumatoid arthritis is superior to that of placebo and similar to that of traditional non-steroidal anti-inflammatory drugs. " 10/01/2004 - "Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials." 07/01/2004 - "We evaluated cardiovascular event data for valdecoxib, a new COX-2-specific inhibitor in approximately 8000 patients with osteoarthritis and rheumatoid arthritis treated with this agent in randomized clinical trials. " 03/01/2005 - "Meta-analysis: upper gastrointestinal tolerability of valdecoxib, a cyclooxygenase-2-specific inhibitor, compared with nonspecific nonsteroidal anti-inflammatory drugs among patients with osteoarthritis and rheumatoid arthritis." Order ALL the reference details at left...
3.	Osteoarthritis 05/01/2007 - "Valdecoxib is a non-steroidal anti-inflammatory drug used in the treatment of rheumatoid and osteoarthritis. " 02/15/2003 - "The analgesic efficacy of valdecoxib at a dose of 10 mg once daily in both osteoarthritis and rheumatoid arthritis is superior to that of placebo and similar to that of traditional non-steroidal anti-inflammatory drugs. " 10/01/2004 - "Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials." 07/01/2004 - "We evaluated cardiovascular event data for valdecoxib, a new COX-2-specific inhibitor in approximately 8000 patients with osteoarthritis and rheumatoid arthritis treated with this agent in randomized clinical trials. " 03/01/2005 - "Meta-analysis: upper gastrointestinal tolerability of valdecoxib, a cyclooxygenase-2-specific inhibitor, compared with nonspecific nonsteroidal anti-inflammatory drugs among patients with osteoarthritis and rheumatoid arthritis." Order ALL the reference details at left...
4.	Postoperative Pain 09/01/2006 - "Analgesic efficacy of valdecoxib for acute postoperative pain after bunionectomy." 09/01/2006 - "Valdecoxib for postoperative pain management after cesarean delivery: a randomized, double-blind, placebo-controlled study." 09/01/2002 - "Preoperative orally administered valdecoxib provides well-tolerated and effective analgesia for mild to moderate postoperative pain." 07/01/2006 - "Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies." 07/01/2003 - "Parecoxib, a prodrug of valdecoxib, a selective COX-2 inhibitor, has been recently introduced for the treatment of moderate to severe postoperative pain. " Order ALL the reference details at left...
5.	Dysmenorrhea (Menstrual Pain) 08/01/2002 - "Valdecoxib, a cyclooxygenase-2-specific inhibitor, is effective in treating primary dysmenorrhea." 01/01/2005 - "Valdecoxib was effective and well tolerated and thus appears to be a viable treatment for menstrual pain due to primary dysmenorrhea." 01/01/2005 - "Valdecoxib for treatment of primary dysmenorrhea. " 08/01/2002 - "Both valdecoxib 20- and 40-mg doses were effective and well tolerated for the treatment of primary dysmenorrhea. " 02/15/2003 - "Valdecoxib is effective in single doses of up to 40 mg for the alleviation of acute menstrual pain and has a rapid onset of action (within 30 min) and a long duration of analgesia (up to 24 h). " Order ALL the reference details at left...

Related Drugs and Biologics

1.	rofecoxib (Vioxx)
2.	Naproxen (Naprosyn)
3.	celecoxib (Celebrex)
4.	parecoxib
5.	Diclofenac (SR 38)
6.	Cyclooxygenase 2 (Cyclooxygenase-2)
7.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
8.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
9.	valdecoxib (Bextra)
10.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)

Related Therapies and Procedures

1.	Analgesia
2.	Laparoscopic Cholecystectomy
3.	Oral Surgery (Maxillofacial Surgery)
4.	Arthroplasty
5.	Combined Modality Therapy

blog comments powered by Disqus

TREATMENT OPTIONS
for Pain,
Ranking and Evidence

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. Analytic charts allow you and your physicians to see at a glance the treatment options—including new, promising, off-label and experimental.

Free Updates for 1 Year
All 11491 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Evidence References
Sample PDF Report on Psoriasis >>

Price:

$24.95 USD & Delivery via PDF download
updates for 1 year

Research Interface PRO

Rapidly retrieve clinical outcome summaries for all evidence of drug efficacy against any disease in seconds. Click "Charts" to view graphs of relative efficacy of all drugs against any known disease. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time. Save hours of search and analysis time:

Two-clicks from Disease to Drug to Evidence: Drill down to full abstract
Enable Experts: Quickly identify key researchers and their publications
Enable FDA Link Generic: Two-clicks to FDA Products/Patents/Generics
Enable Export: All outcome statements and scores exportable to Excel/TSV for automated meta-analysis
Research Network: Explore drug and disease relationships visually
Enable Mobile Interface: Access from your cellphone, iPhone or PDA

Price:

$490.00 USD access via web interface
1 year subscription

Request Bulk Institution License Details >>