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Sex, life, and death in MYC-driven lymphomagenesis.

Abstract
Gong et al. (2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently induced for disease progression.
AuthorsChi V Dang
JournalMolecular cell (Mol Cell) Vol. 81 Issue 19 Pg. 3886-3887 (10 07 2021) ISSN: 1097-4164 [Electronic] United States
PMID34624215 (Publication Type: Journal Article)
CopyrightCopyright © 2021 Elsevier Inc. All rights reserved.
Chemical References
  • DEAD-box RNA Helicases
Topics
  • DEAD-box RNA Helicases
  • Humans
  • Lymphoma
  • Male

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