Radioiodine therapy induced sialadenitis versus chronic idiopathic sialadenitis-Presentation and outcomes.

Abstract

BACKGROUND:

This study explores the unique characters of high dose radioactive iodine (RAI) induced chronic sialadenitis.

METHODS:

A retrospective study of patients having received salivary endoscopy and followed in our outpatient clinic.

RESULTS:

A total of 100 patients met the inclusion criteria, 75 were diagnosed with chronic idiopathic sialoadenitis and 25 with radio-iodine induced sialoadenitis (RIS). The main complaint in both groups was swelling of the parotid gland. Pain, dysphagia, and xerostomia were observed considerably more in the RIS group. During sialo-endoscopy, fibrosis of the Stensen's duct was more common in the RIS group (p = 0.003). RIS patients group generally managed better with interventional endoscopic treatment alone (80% vs. 46%).

CONCLUSION:

RIS patients have distinct clinical characteristics. There may be a collateral muscular damage to the masticatory muscles. Fibrosis and parenchymal damage are major findings during sialendoscopy. Sialendoscopy is a safe and efficient treatment for RAI induced sialadenitis.

• Authors: Hanna Gilat, Igor Vainer, Gal Avishai, Shiri L Maymon, Uri Alkan, Roy Hod, Eyal Robenshtock, Sivan Friedman, Thomas Shpitzer
• Journal: Head & neck (Head Neck) Vol. 43 Issue 9 Pg. 2724-2730 (09 2021) ISSN: 1097-0347 [Electronic] United States
• PMID: 34042252 (Publication Type: Journal Article)
• Copyright: © 2021 Wiley Periodicals LLC.

Chemical References

• Iodine Radioisotopes

Topics

• Endoscopy
• Humans
• Iodine Radioisotopes (adverse effects)
• Retrospective Studies
• Salivary Ducts
• Sialadenitis (diagnosis, etiology)
• Thyroid Neoplasms
• Treatment Outcome