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Myoclonus and hypersensitivity of the hind limbs and tail with urinary retention following neuraxial administration of morphine in a cat.

Abstract
An adult female domestic shorthair cat developed myoclonus, muscle rigidity, and hypersensitivity of the hind limbs and tail with urinary retention following neuraxial administration of morphine. Myoclonic contractions resolved following treatment with midazolam and a urinary catheter was placed until normal micturition returned. The cat was clinically normal 36 hours after neuraxial morphine injection. The cat underwent a second surgery without neuraxial morphine and control of postoperative pain required more intervention. Key clinical message: Neuraxial morphine may cause myoclonus and urinary retention. The response to pharmacological treatment of myoclonus is varied, but a benzodiazepine drug may be effective.
AuthorsMasako Fujiyama, Justin Lavallée, Kerrie Lewis, Tanya Duke-Novakovski
JournalThe Canadian veterinary journal = La revue veterinaire canadienne (Can Vet J) Vol. 62 Issue 4 Pg. 389-392 (04 2021) ISSN: 0008-5286 [Print] Canada
PMID33867552 (Publication Type: Case Reports)
CopyrightCopyright and/or publishing rights held by the Canadian Veterinary Medical Association.
Chemical References
  • Analgesics, Opioid
  • Morphine
Topics
  • Analgesics, Opioid (adverse effects)
  • Animals
  • Cat Diseases (chemically induced, drug therapy)
  • Cats
  • Female
  • Morphine (adverse effects)
  • Myoclonus (chemically induced, drug therapy, veterinary)
  • Tail
  • Urinary Retention (chemically induced, veterinary)

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