[Conservative treatment of breast cancer].

Abstract

The paper is concerned with clinical characterization of 81 breast cancer patients after conservative radio- and hormonotherapy. Of the total number of patients 47 suffered from inoperable tumors as a result of local spreading, 30 patients had serious contraindications for the operation, and 4 patients refused surgical intervention. Of the total number of patients 85% were aged over 50, 69%--over 60.41%--over 70, and 4 patients--over 80. The results of radiotherapy after a radical program and administration of antiestrogens (tamoxifen, zitosonium) were evaluated in 71 patients: in 42 tumors were undetectable, in 16 they were reduced by more than 50% of their primary size. An analysis of short-term results during 1-year follow-up showed that of 50 patients complete remission was observed in 24, stabilization of a tumor process was achieved in 8. The results should be regarded as promising with relation to the patients' age, status, tumor spreading, and concomitant diseases.

• Authors: M M Nivinskaia, V P Letiagin, L I Chebotareva, V M Ivanov, I D Klykova
• Journal: Meditsinskaia radiologiia (Med Radiol (Mosk)) Vol. 33 Issue 5 Pg. 5-9 (May 1988) ISSN: 0025-8334 [Print] Russia (Federation)
• Vernacular Title: Konservatnoe lechenie raka molochnoĭ zhelezy.
• PMID: 3374304 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Estrogen Antagonists
• Organic Chemicals
• Tamoxifen
• zitosonium

Topics

• Adult
• Aged
• Aged, 80 and over
• Breast Neoplasms (drug therapy, radiotherapy)
• Combined Modality Therapy
• Estrogen Antagonists (therapeutic use)
• Female
• Humans
• Middle Aged
• Organic Chemicals
• Tamoxifen (therapeutic use)