Drug-induced enterocolitis syndrome: Similarities and differences compared with food protein-induced enterocolitis syndrome.

Abstract

In 2014, drug-induced enterocolitis syndrome (DIES) was described for the first time. It is still a poorly known disease with symptoms that typically resemble those of food protein-induced enterocolitis syndrome (FPIES). To date, six more cases of DIES have been described and new clinical diagnostic criteria have been proposed based on those in the international guidelines for FPIES. In this paper, the authors describe three more cases of DIES. In addition, similarities and differences with FPIES have been deeply analyzed. To date, several unanswered questions need to be addressed, but clinicians must be instructed how to identify DIES, in order to make an allergy workup and give definite therapeutic indications to patients, especially in children where DIES seems to be more frequent.

• Authors: Francesca Mori, Giulia Liccioli, Oliver Fuchs, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Elio Novembre, Jean-Christoph Caubet
• Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (Pediatr Allergy Immunol) Vol. 32 Issue 6 Pg. 1165-1172 (08 2021) ISSN: 1399-3038 [Electronic] England
• PMID: 33651420 (Publication Type: Journal Article)
• Copyright: © 2021 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Chemical References

• Dietary Proteins
• Pharmaceutical Preparations

Topics

• Child
• Dietary Proteins (adverse effects)
• Enterocolitis (diagnosis)
• Food Hypersensitivity (diagnosis)
• Humans
• Infant
• Pharmaceutical Preparations
• Syndrome