Application of a novel carboxymethyl cellulose-based Mohs sol-gel on malignant wounds in three dogs.

Abstract

The preparation of modified Mohs paste, commonly used for malignant wounds, requires time and effort. Moreover, metal-containing liquid waste is generated when malignant wounds are scrubbed. Therefore, we previously changed the base material of the modified Mohs paste from zinc oxide starch powder to carboxymethyl cellulose (CMC). The novel modified Mohs paste based on CMC (moM-CMC sol) may reduce these disadvantages. In the present study, the moM-CMC sol was applied to malignant tumors in three dogs to manage bleeding and malodor. The moM-CMC sol transitioned into a gel on the tumors within an hour of application and could be easily removed. The symptoms resolved in all cases. The moM-CMC sol could be beneficial for dogs with malignant wounds.

• Authors: Yasuhiro Fukuyama, Takuya Maruo, Yuta Nishiyama, Yuki Nemoto, Kaho Murayama, Hideki Kayanuma, Shinpei Kawarai
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 83 Issue 3 Pg. 385-389 (Mar 11 2021) ISSN: 1347-7439 [Electronic] Japan
• PMID: 33441500 (Publication Type: Journal Article)

Chemical References

• Starch
• Carboxymethylcellulose Sodium

Topics

• Animals
• Carboxymethylcellulose Sodium
• Dog Diseases (drug therapy, surgery)
• Dogs
• Neoplasms (veterinary)
• Starch