We present the case of a 67-year-old man with
diarrhea for more than 5 mo whose colonoscopy in another hospital showed multiple
colonic polyps, which indicated moderate to severe dysplasia and focal early
cancer. Therefore, he was referred to our hospital for further endoscopic treatment. Colonoscopy after admission showed that the mucosa of the terminal ileum and the entire colon were slightly swollen and finely granular. Endoscopic mucosal resection was performed for
colonic polyps located in the liver flexure of the colon and descending colon, respectively. Histopathological findings revealed diffuse infiltration of medium-sized lymphoid cells in the colonic mucosa and visible lymphoepithelial lesions. The histopathology of the
polyp in the descending colon indicated moderately differentiated
adenocarcinoma limited to the mucosa with negative
resection margins. Additionally, immunohistochemical analysis showed positive staining for CD7 and CD8. Therefore, we arrived at a diagnosis of EATL with early
colon cancer. Subsequently, the patient was transferred to the hematology department for
chemotherapy. The patient's
diarrhea was not significantly relieved after receiving
chemotherapy, and he ultimately died of severe myelosuppression.
CONCLUSION: