Infantile toxic epidermal necrolysis: Successful treatment of an 8-week-old with intravenous immunoglobulin and amniotic membrane transplant.

Abstract

Stevens-Johnson syndrome and toxic epidermal necrolysis comprise a spectrum of severe mucocutaneous hypersensitivity reactions. A paucity of data limits current understanding of the etiology, treatment options, and prognosis of this entity in the infantile population compared to that in the adult and pediatric literature. We describe the case of an 8-week-old male with toxic epidermal necrolysis treated successfully with intravenous immunoglobulin and amniotic membrane transplant. This patient is the youngest surviving infant with toxic epidermal necrolysis to be reported.

• Authors: Janelle S Nassim, Sabrina A Karim, Pierre-Olivier Grenier, Birgitta Schmidt, Krystal M Jones
• Journal: Pediatric dermatology (Pediatr Dermatol) Vol. 38 Issue 1 Pg. 202-205 (Jan 2021) ISSN: 1525-1470 [Electronic] United States
• PMID: 33125180 (Publication Type: Case Reports)
• Copyright: © 2020 Wiley Periodicals LLC.

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adult
• Amnion
• Child
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Infant
• Male
• Stevens-Johnson Syndrome (diagnosis, drug therapy, etiology)