Abstract | OBJECTIVE: MATERIALS AND METHODS:
DNA-binding ability of a pathogenic IKZF variant was tested using electrophoretic mobility shift assay and PC localization of the variant was assessed by immunofluorescent microscopy in NIH3T3 cells. RESULTS: CONCLUSIONS:
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Authors | Ebru Yilmaz, Hye S Kuehn, Eda Odakir, Julie E Niemela, Alper Ozcan, Ahmet Eken, Meino Rohlfs, Murat Cansever, Veysel Gok, Firdevs Aydin, Musa Karakukcu, Fabian Hauck, Christoph Klein, Ekrem Unal, Sergio D Rosenzweig, Turkan Patiroglu |
Journal | Journal of pediatric hematology/oncology
(J Pediatr Hematol Oncol)
Vol. 43
Issue 3
Pg. e351-e357
(04 01 2021)
ISSN: 1536-3678 [Electronic] United States |
PMID | 33122583
(Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved. |
Chemical References |
- IKZF1 protein, human
- Ikaros Transcription Factor
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Topics |
- Anemia, Hemolytic, Autoimmune
(complications, genetics, therapy)
- Animals
- Common Variable Immunodeficiency
(complications, genetics, therapy)
- Hematopoietic Stem Cell Transplantation
- Humans
- Ikaros Transcription Factor
(genetics)
- Infant
- Male
- Mice
- NIH 3T3 Cells
- Pancytopenia
(complications, genetics, therapy)
- Point Mutation
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