Most of the reported field effect transistors (
FETs) fall short of a general method to uniquely specify and detect a target analyte. For this reason, we propose a
pentacene-based FET with a
graphene oxide support system (GOSS), composed of functionalized
graphene oxide (GO) ink. The GOSS with a specific moiety group to capture the
biomaterial of interest was inkjet printed on the
pentacene FET. It provided modular receptor sites on the surface of
pentacene, without alteration of the device. To evaluate the performance of a GOSS-
pentacene FET biosensor, we detected the artificial
DNA and
circulating tumor cells as a proof-of-concept. The mobility of the FET dramatically changed upon capturing the target biomolecule on the GOSS. The FET exhibited high selectivity with 0.1 pmoles of the target
DNA and a few
cancer cells per detection volume. This study suggests a valuable sensor for medical diagnosis that can be mass produced effortlessly at low-cost.