Albumin: Indications in chronic liver disease.

Abstract

Albumin is currently employed as a plasma expander to prevent and treat specific complications of cirrhosis with ascites, such as the prevention of paracentesis-induced circulatory dysfunction and renal dysfunction induced by spontaneous bacterial peritonitis, as well as the diagnosis and treatment of acute kidney injury and hepatorenal syndrome. Recently, evidence has shown that long-term albumin administration in patients with decompensated cirrhosis reduces mortality and incidence of complications, eases the management of ascites, is cost effective, and has a good safety profile.

• Authors: Manuel Tufoni, Giacomo Zaccherini, Paolo Caraceni, Mauro Bernardi
• Journal: United European gastroenterology journal (United European Gastroenterol J) Vol. 8 Issue 5 Pg. 528-535 (06 2020) ISSN: 2050-6414 [Electronic] England
• PMID: 32213034 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Diuretics
• Serum Albumin, Human

Topics

• Acute Kidney Injury (diagnosis, etiology, prevention & control)
• Aged
• Ascites (diagnosis, etiology, therapy)
• Chronic Disease (therapy)
• Diuretics (administration & dosage)
• Drug Administration Schedule
• Female
• Hepatorenal Syndrome (diagnosis, etiology, prevention & control)
• Humans
• Infusions, Intravenous
• Leukocyte Count
• Liver Cirrhosis (complications, diagnosis, therapy)
• Paracentesis
• Peritonitis (diagnosis, etiology, prevention & control)
• Serum Albumin, Human (administration & dosage)
• Severity of Illness Index
• Treatment Outcome