HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Surgical versus conservative management of ankle fractures in adults: A systematic review and meta-analysis.

AbstractAIMS:
This study compared outcomes of surgical versus conservative management of ankle fractures in adults through a systematic review and meta-analysis.
METHODS:
We searched CINAHL, EMBASE, MEDLINE and CENTRAL databases (1946-June 2019) for randomised and quasi-randomised controlled trials comparing surgical versus conservative management of closed adult ankle fractures of any type. Estimates of effect were pooled using random effects meta-analysis.
RESULTS:
1153 patients from 7 trials were included. Our primary outcome, ankle function score, was not statistically significantly different at 6-months (pooled mean difference (surgical minus conservative) = 1.0; 95% CI: -2.3 to 4.3; p = 0.55) or 12-months or more (pooled mean difference = 4.6; 95% CI: -1.0 to 10.2; p = 0.11) between surgical and conservative groups in three trials assessing displaced or unstable fractures, and two trials using non-validated questionnaires. One trial assessing AO-type-B1 fractures without talar shift had a statistically significant difference favouring conservative management, which was not clinically meaningful. Surgery had lower rates of early treatment failure and malunion/non-union, but higher rates of further surgery and infection.
CONCLUSIONS:
Surgical and conservative management of displaced or unstable ankle fractures produce similar short-term functional outcomes. The higher risk of early treatment failure and malunion/non-union in the conservative group versus higher rates of further surgery and infection in the surgical group should be considered. Trials are needed to assess longer-term results and inform management of select patient groups.
AuthorsOmar A Javed, Qasim A Javed, Obioha C Ukoumunne, Livio Di Mascio
JournalFoot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons (Foot Ankle Surg) Vol. 26 Issue 7 Pg. 723-735 (Oct 2020) ISSN: 1460-9584 [Electronic] France
PMID31818542 (Publication Type: Journal Article, Meta-Analysis, Systematic Review)
CopyrightCopyright © 2019 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.
Topics
  • Ankle Fractures (therapy)
  • Bandages
  • Conservative Treatment (methods)
  • Fracture Fixation (methods)
  • Humans
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: