Abstract | OBJECTIVE: METHODS: The randomised clinical trial was conducted at Kharadar General Hospital, Karachi, from Dec 2016 to Nov 2017. Children aged 6 to 60 months, clinically presented with allergic rhinitis were included in the study. Total 212 children, randomized into intervention group A (received probiotic LP-33) and control group B (received cetirizine) for six weeks, were included in the analysis. Baseline allergic rhinitis symptoms ( rhinorrhea, sneezing, nasal blocking, coughing, feeding & sleeping difficulties) were assessed after two and six weeks follow up and correlated both groups by using Pearson chi-square test. A p value of <0.05 were considered statistically significant. RESULTS: Total 212 children were analysed, out of them 113 (53.3%) were male. Mean age of study participant was 26 ± 16.64 months and mean body weight was 10.1 ± 3.26 Kg. More than 95% cases have shown significant improvement in their baseline symptoms ( rhinorrhea, sneezing, nasal blocking, coughing, feeding difficulties and sleeping difficulties) in both intervention (L-33 Probiotic) and control ( Cetirizine) groups. Statistically there was no difference in effectiveness of probiotic and cetirizine treatment for perennial allergic rhinitis (P > 0.05). CONCLUSIONS:
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Authors | Mubashir Ahmed, Abdul Gaffar Billoo, Khalid Iqbal |
Journal | Pakistan journal of medical sciences
(Pak J Med Sci)
2019 Nov-Dec
Vol. 35
Issue 6
Pg. 1538-1543
ISSN: 1682-024X [Print] Pakistan |
PMID | 31777489
(Publication Type: Journal Article)
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Copyright | Copyright: © Pakistan Journal of Medical Sciences. |