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Carboplatin-associated Cranial Neuropathy.

Abstract
Carboplatin is a platinum-based chemotherapeutic agent used for the treatment of many solid tumors. Peripheral neuropathy is a common side effect; but, to our knowledge, ocular motor cranial neuropathies have not been reported in the literature. We describe a case of persistent third and fourth nerve palsies after systemic administration of intra-arterial carboplatin for glioblastoma multiforme. Neither nerve regained function after carboplatin was stopped.
AuthorsShanlee M Stevens, Collin M McClelland, John E Trusheim, Michael S Lee
JournalNeuro-ophthalmology (Aeolus Press) (Neuroophthalmology) Vol. 42 Issue 5 Pg. 302-305 (Oct 2018) ISSN: 0165-8107 [Print] England
PMID30258477 (Publication Type: Case Reports)

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