Abstract | BACKGROUND: METHODS: We will electronically search all potential citations in PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) from their inception to April 2018. The randomized controlled trials, which investigated the efficacy of oral zinc sulfate for chemotherapy-induced oral mucositis will be considered. We will assign 2 independent investigators to perform search, screen citations, extract data, and appraise risk of bias. And then, the primary investigator will adopt RevMan 5.3 software to complete all statistical analyses. ETHICS AND DISSEMINATION: The findings from this systematic review and meta-analysis will be submitted to a peer-reviewed journal for publication. Moreover, we will disseminate all results in any topic-related conference. REGISTRATION NUMBER: This protocol has been registered with a number of CRD42018093605.
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Authors | Xu Tian, Wei-Qing Chen, Xiao-Ling Liu, Yuan-Ping Pi, Hui Chen |
Journal | Medicine
(Medicine (Baltimore))
Vol. 97
Issue 21
Pg. e10839
(May 2018)
ISSN: 1536-5964 [Electronic] United States |
PMID | 29794779
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
- Antineoplastic Agents
- Astringents
- Zinc Sulfate
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Topics |
- Antineoplastic Agents
(adverse effects)
- Astringents
(administration & dosage, therapeutic use)
- Humans
- Neoplasms
(complications, drug therapy)
- Randomized Controlled Trials as Topic
- Stomatitis
(chemically induced, drug therapy, prevention & control)
- Systematic Reviews as Topic
- Zinc Sulfate
(administration & dosage, therapeutic use)
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