A successful aggressive surgical and medical approach to pulmonary artery obstruction due to Mycobacterium abscessus infection post lung transplantation.

Abstract

Mycobacterium abscessus infection following lung transplantation has historically been associated with poor outcomes. We report a case of bilateral lung retransplantation complicated by obstruction of the right pulmonary artery secondary to M. abscessus mycotic aneurysm. Aggressive surgical management, including reconstruction of the right pulmonary artery, was undertaken with prolonged antimicrobial therapy. Thirty-six months later, antibiotics have been discontinued and the patient has stable soft tissue chest wall disease with good graft function. Mortality and morbidity associated with M. abscessus infection is considerable but this case illustrates that with aggressive early management, outcomes may be favorable.

• Authors: Sakhee Kotecha, Olivia C Smibert, Atsuo Doi, Julian Gooi, Orla Morrissey, Miranda Paraskeva, Greg I Snell, David McGiffin
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 20 Issue 2 Pg. e12838 (Apr 2018) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 29359876 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Anti-Bacterial Agents

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage, therapeutic use)
• Humans
• Lung Transplantation (adverse effects)
• Male
• Mycobacterium Infections, Nontuberculous (etiology, therapy)
• Mycobacterium abscessus
• Postoperative Complications (therapy)
• Pulmonary Artery (microbiology, pathology, surgery)