Abstract | PURPOSE: METHODS: We conducted a cross-sectional survey among postmenopausal, HR+ BCS who previously took or were currently taking AIs. The primary outcome was patients' perception of living with chronic pain over the past 6 months. We measured pain and demographic and clinical variables. Multivariable logistic regression analysis was performed to evaluate risk factors associated with the perception of chronic pain. RESULTS: Among 1280 participants, 167 (13%) reported having the perception of living with chronic pain before their breast cancer diagnosis; 426 (34%) reported this perception after completion of non-hormonal cancer treatment. Seventy-eight percent of BCSs reported experiencing at least one type of treatment-related pain within the past 7 days, with 23% experiencing at least three types. The most common types of pain were AI-induced musculoskeletal pain (49%) and pain at the surgery or radiation site (31%). Younger age (< 56), BMI > 25, and the perception of living with chronic pain before diagnosis were risk factors associated with the perception of living with chronic pain. CONCLUSIONS: One in three postmenopausal, HR+ BCS considered themselves to be living with chronic pain. Effective interventions to reduce chronic pain are needed.
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Authors | Ting Bao, Andrew Seidman, Qing Li, Christina Seluzicki, Victoria Blinder, Salimah H Meghani, John T Farrar, Jun J Mao |
Journal | Breast cancer research and treatment
(Breast Cancer Res Treat)
Vol. 169
Issue 1
Pg. 133-140
(May 2018)
ISSN: 1573-7217 [Electronic] Netherlands |
PMID | 29350307
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Aromatase Inhibitors
(adverse effects, therapeutic use)
- Breast
(drug effects, physiopathology)
- Breast Neoplasms
(complications, drug therapy, epidemiology, physiopathology)
- Cancer Survivors
- Chronic Pain
(epidemiology, etiology, physiopathology)
- Cross-Sectional Studies
- Female
- Humans
- Middle Aged
- Musculoskeletal Pain
(epidemiology, etiology, physiopathology)
- Risk Factors
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