Phosphazide (nikavir) is a highly effective drug for the treatment of HIV/AIDS infection.

Abstract

Federation Convincing evidence for high therapeutic activity and tolerability of Phosphazide in the treatment of HIV/AIDS-infection is given. Phosphazide is currently used in various regimens of highly active antiretroviral therapy, as well as in the HIV therapy in patients with simultaneously acquired chronic hepatitis C or tuberculosis. Therapeutic possibilities of Phosphazide were clearly manifested in the prevention of HIV transmission from mother to child. There is every reason to use Phosphazide in first-line antiretroviral therapy.

• Authors: George A Galegov
• Journal: Voprosy virusologii (Vopr Virusol) 2017 Vol. 62 Issue 1 Pg. 5-11 ISSN: 0507-4088 [Print] Russia (Federation)
• PMID: 29323840 (Publication Type: Journal Article, Review)

Chemical References

• 3'-azido-2',3'-dideoxythymidine 5'-H-phoshonate
• Anti-HIV Agents
• Organophosphonates
• Zidovudine

Topics

• Anti-HIV Agents (pharmacokinetics, therapeutic use)
• Antiretroviral Therapy, Highly Active (methods)
• Female
• Fetus
• HIV (drug effects, genetics, metabolism)
• HIV Infections (drug therapy, transmission, virology)
• Humans
• Infectious Disease Transmission, Vertical (prevention & control)
• Organophosphonates (pharmacokinetics, therapeutic use)
• Pregnancy
• Pregnancy Complications, Infectious (drug therapy, virology)
• Treatment Outcome
• Zidovudine (analogs & derivatives, pharmacokinetics, therapeutic use)