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Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a noncytotoxic regimen.

Abstract
Pyoderma gangrenosum (PG) is a morbid necrotizing neutrophilic dermatoses for which current treatments are inadequate. Here, we describe the use of a novel noncytotoxic regimen of the deoxycytidine analog decitabine to treat underlying myeloid malignancy causing PG, to thereby produce safe and effective resolution of extensive PG.
AuthorsMostafa F M Saleh, Yogen Saunthararajah
JournalClinical case reports (Clin Case Rep) Vol. 5 Issue 12 Pg. 2025-2027 (12 2017) ISSN: 2050-0904 [Print] England
PMID29225849 (Publication Type: Case Reports)

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