Abstract | BACKGROUND: The use of combined positron emission tomography/computed tomography for staging in patients with cancer and the widespread use of magnetic resonance imaging has led to increased detection of incidental sellar masses. The imaging findings can be suggestive of a benign pituitary tumor, but metastasis can never be completely ruled out with noninvasive work-up. Appropriate diagnosis of sellar masses is critical, as the treatment paradigm might change in the presence of a pituitary metastasis. Definitive tissue diagnosis might prevent unnecessary radiotherapy to the skull base or the need for systemic treatment when benign pituitary disease is confirmed. METHODS: A retrospective chart review from 2010 to 2015 of all patients with recently diagnosed cancer and undergoing surgery for sellar region masses was performed. RESULTS: CONCLUSIONS: Surgical resection of a sellar mass in patients with known cancer helps in the definitive diagnosis, relieves compressive symptoms, and avoids unnecessary empiric radiotherapy in cases of confirmed benign pituitary disease.
|
Authors | Carlos R Goulart, Smita Upadhyay, Leo F S Ditzel Filho, Andre Beer-Furlan, Ricardo L Carrau, Luciano M Prevedello, Daniel M Prevedello |
Journal | World neurosurgery
(World Neurosurg)
Vol. 106
Pg. 254-265
(Oct 2017)
ISSN: 1878-8769 [Electronic] United States |
PMID | 28673886
(Publication Type: Journal Article)
|
Copyright | Copyright © 2017 Elsevier Inc. All rights reserved. |
Topics |
- Adenocarcinoma
(diagnostic imaging, secondary)
- Adenocarcinoma, Follicular
(diagnostic imaging, secondary)
- Adenoma
(diagnostic imaging, pathology)
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
(pathology)
- Carcinoma, Non-Small-Cell Lung
(diagnostic imaging, secondary)
- Carcinoma, Renal Cell
(diagnostic imaging, secondary)
- Colorectal Neoplasms
(pathology)
- Diagnosis, Differential
- Female
- Granular Cell Tumor
(diagnostic imaging, pathology)
- Humans
- Incidental Findings
- Kidney Neoplasms
(pathology)
- Lung Neoplasms
(pathology)
- Magnetic Resonance Imaging
- Male
- Melanoma
(diagnostic imaging, secondary)
- Middle Aged
- Neoplasm Metastasis
(diagnostic imaging, pathology)
- Neoplasm Staging
- Neuroendocrine Tumors
(diagnostic imaging, secondary)
- Pituitary Neoplasms
(diagnostic imaging, pathology, secondary)
- Positron Emission Tomography Computed Tomography
- Retrospective Studies
- Skin Neoplasms
(pathology)
- Thyroid Neoplasms
(pathology)
|