Total resection combined with osteotomy is more effective for orbital solitary fibrous tumor excision: a report of three cases.

Abstract

A solitary fibrous tumor is a neoplasm generally arising from the mesothelial surfaces of the pleura and mesothelium. In this paper, we describe three cases of rare solitary fibrous tumors arising from the orbit and discuss the management of the tumors, including diagnosis and treatment. All three cases were treated by surgical resection and showed satisfactory aesthetic and functional results. For a definitive diagnosis, immunohistochemical staining for proteins such as vimentin, CD34 and bcl-2 and hematoxylin and eosin (H&E) staining for identifying the morphological characteristics of spindle cell tumors with a partially storiform pattern and staghorn vessels are indispensable. The principle of treatment for orbital solitary fibrous tumor is complete resection because the prognosis depends on controlling tumor progression, which can be difficult with chemotherapy and radiotherapy alone.

• Authors: Katsuya Tanaka, Hiroki Yano, Hiroko Hayashi, Akiyoshi Hirano
• Journal: International ophthalmology (Int Ophthalmol) Vol. 38 Issue 1 Pg. 345-351 (Feb 2018) ISSN: 1573-2630 [Electronic] Netherlands
• PMID: 28054210 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antigens, CD34
• Biomarkers, Tumor
• Vimentin

Topics

• Adult
• Aged
• Antigens, CD34 (metabolism)
• Biomarkers, Tumor (metabolism)
• Diagnosis, Differential
• Female
• Humans
• Immunohistochemistry
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Ophthalmologic Surgical Procedures (methods)
• Orbital Neoplasms (diagnosis, metabolism, surgery)
• Osteotomy (methods)
• Solitary Fibrous Tumors (diagnosis, metabolism, surgery)
• Tomography, X-Ray Computed
• Vimentin (metabolism)