Successful Treatment of Brachial Plexopathy Due to Herpes Zoster Infection With Intravenous Immunoglobulin.

Abstract

OBJECTIVE:

The aim of this study was to report the case of a male patient with Parkinson disease who developed brachial plexopathy (BP) due to varicella-zoster virus, which was successfully treated with human immunoglobulin.

METHOD:

We report the case of a 75-year-old male subject with a diagnosis of Parkinson disease who came to our hospital complaining of pain, skin lesions, and strength loss in his right arm during the past 2 months. Physical examination revealed vesicular rash compatible with varicella-zoster virus lesions. Nerve conduction studies and magnetic resonance imaging of the brachial plexus showed inflammatory changes at that level. A trial with oral valacyclovir followed by intravenous methylprednisolone bolus was administered without further response. However, human intravenous immunoglobulin resulted in complete recovery of the symptoms.

CONCLUSIONS:

Human immunoglobulin is effective in BP due to zoster infection and must be considered if standard treatment fails. To the best of our knowledge, this is the first report of BP associated to zoster infection successfully treated with intravenous immunoglobulin.

• Authors: Michel Sáenz-Farret, Valeria Sandoval-Rodríguez, Claudia Esther Paz-Navarro, Carlos Zúñiga-Ramírez
• Journal: Clinical neuropharmacology (Clin Neuropharmacol) 2017 Jan/Feb Vol. 40 Issue 1 Pg. 43-47 ISSN: 1537-162X [Electronic] United States
• PMID: 27879550 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Aged
• Brachial Plexus Neuropathies (diagnostic imaging, drug therapy, etiology, virology)
• Encephalitis, Varicella Zoster (complications, diagnostic imaging)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Magnetic Resonance Imaging
• Male
• Neural Conduction (drug effects)
• Parkinson Disease (complications)