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[The engineered thymidylate kinase (TMPK)/azidothymidine (AZT)-axis offers efficient bystander cell killing effect for suicide gene therapy for cancer].

AuthorsTakeya Sato, Teruyuki Yanagisawa
JournalNihon yakurigaku zasshi. Folia pharmacologica Japonica (Nihon Yakurigaku Zasshi) Vol. 147 Issue 6 Pg. 326-9 (Jun 2016) ISSN: 0015-5691 [Print] Japan
PMID27301304 (Publication Type: Journal Article)
Chemical References
  • Zidovudine
  • Nucleoside-Phosphate Kinase
  • dTMP kinase
Topics
  • Animals
  • Apoptosis
  • Bystander Effect
  • Genetic Therapy
  • Humans
  • Neoplasms (enzymology, genetics, pathology, therapy)
  • Nucleoside-Phosphate Kinase (metabolism)
  • Zidovudine (therapeutic use)

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