Abstract | BACKGROUND AND PURPOSE: METHODS: We used a Taiwan national insurance claims data set of 1 million enrollees to distinguish 61,899 patients with RN and 123,798 randomly selected age- and sex-matched controls from January 1, 2000, to December 31, 2010. Both cohorts were followed up until the occurrence of stroke or the end of follow-up. The risk of AIS was evaluated by using the Cox proportional hazards regression model. RESULTS: After adjustment of the relevant covariates, the RN group showed a lower risk of AIS (adjusted hazard ratio [aHR] 0.74 [95% confidence interval {CI}, 0.70-0.79]) compared with the control cohort at the end of follow-up. Among the participants without comorbidities, the RN cohort still had a lower risk of AIS compared with the control cohort (aHR 0.69 [95% CI, 0.59-0.81]). Moreover, in the three stratified age groups, RN was associated with a significantly decreased risk of AIS (ages ≤49 years: aHR 0.77 [95% CI, 0.63-0.95]; ages 50-64 years: aHR 0.72 [95% CI, 0.64-0.81]; ages ≥65 years: aHR 0.78 [95% CI, 0.71-0.85]). CONCLUSIONS: RN was associated with a decreased risk of developing AIS. Although a reduction in risk of AIS was observed, it warrants further consideration to prevent AIS in patients with RN.
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Authors | Chun-Hung Tseng, Jiunn-Horng Chen, Cheng-Li Lin, Chia-Hung Kao |
Journal | Allergy and asthma proceedings
(Allergy Asthma Proc)
2015 Nov-Dec
Vol. 36
Issue 6
Pg. e106-12
ISSN: 1539-6304 [Electronic] United States |
PMID | 26534741
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Comorbidity
- Databases, Factual
- Female
- Humans
- Incidence
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Outcome Assessment, Health Care
- Population Surveillance
- Proportional Hazards Models
- Retrospective Studies
- Rhinitis
(complications, epidemiology)
- Risk
- Stroke
(complications, epidemiology)
- Taiwan
(epidemiology)
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