Astroblastoma of cerebrum: A rare case report and review of literature.

Abstract

Astroblastoma is a rare neuroepithelial primary brain tumor of uncertain origin. They form 0.45-2.8% of all the neuroglial tumors. This tumor is usually localized in the cerebral hemisphere of young adults and children. The authors report a case of low-grade astroblastoma in a 16-year-old male and review the relevant literature. The patient presented with 2 months history of progressive headache with projectile vomiting for last 2 months. He underwent gross total resection of the lesion through right temporo-occipital craniotomy. Since tumor showed no evidence of high-grade lesion, adjuvant radiotherapy was not planned. However, the patient developed recurrence of the tumor after 12 months. Localized three-dimensional conformal radiotherapy was planned. In patients harboring anaplastic astroblastoma, gross-total resection and adjuvant therapy after the initial surgery seems to be the best choice. They can be easily misdiagnosed as they are rarely encountered in clinical practice and share common radiological and histopathologic appearance with other glial neoplasms.

• Authors: Satya Narayan, Akhil Kapoor, Mukesh Kumar Singhal, Shankar Lal Jakhar, Puneet Kumar Bagri, Prakash Singh Rajput, Harvindra Singh Kumar
• Journal: Journal of cancer research and therapeutics (J Cancer Res Ther) 2015 Jul-Sep Vol. 11 Issue 3 Pg. 667 ISSN: 1998-4138 [Electronic] India
• PMID: 26458709 (Publication Type: Case Reports, Letter, Review)

Topics

• Adolescent
• Brain Neoplasms (diagnostic imaging, pathology, surgery)
• Humans
• Male
• Neoplasm Recurrence, Local (diagnostic imaging, prevention & control)
• Neoplasms, Neuroepithelial (diagnostic imaging, pathology, surgery)
• Occipital Lobe (diagnostic imaging, pathology)
• Radiography
• Treatment Outcome