Ceftriaxone susceptibility of oxacillin-susceptible Staphylococcus aureus from patients with prosthetic joint infection.

Abstract

Ceftriaxone is used to treat oxacillin-susceptible S. aureus (OSSA) prosthetic joint infection (PJI). Susceptibility of ceftriaxone against OSSA has been questioned. Ceftriaxone susceptibility was determined against 100 PJI OSSA isolates. Ceftriaxone MIC90/MIC50 were 8/4 and 4/3μg/mL by broth microdilution and Etest, respectively. Ceftriaxone susceptibility is inferable by oxacillin susceptibility.

• Authors: Kerryl E Greenwood-Quaintance, Peggy Kohner, Douglas R Osmon, Abinash Virk, Robin Patel
• Journal: Diagnostic microbiology and infectious disease (Diagn Microbiol Infect Dis) Vol. 82 Issue 2 Pg. 177-8 (Jun 2015) ISSN: 1879-0070 [Electronic] United States
• PMID: 25842182 (Publication Type: Journal Article)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Chemical References

• Anti-Bacterial Agents
• Ceftriaxone
• Oxacillin

Topics

• Anti-Bacterial Agents (pharmacology)
• Arthritis, Infectious (microbiology)
• Ceftriaxone (pharmacology)
• Humans
• Microbial Sensitivity Tests
• Oxacillin (pharmacology)
• Prosthesis-Related Infections (microbiology)
• Staphylococcal Infections (microbiology)
• Staphylococcus aureus (drug effects, isolation & purification)