Recurrent mitral valve regurgitation with neutrophil infiltration in a patient with multiple aseptic abscesses.

Abstract

Aseptic abscess (AA) is characterized by accumulation of neutrophils without evidence of infection, no response to antibiotics, and rapid response to corticosteroids. We report a case of multiple abscesses in the subcutaneous tissues and joints, and severe mitral valve regurgitation. Although AA did not respond to antibiotic therapy, it improved dramatically with corticosteroid treatment. However, repeated valvuloplasty was required for the mitral valve regurgitation. The mitral valve tissue showed neutrophil infiltration without any bacterial invasion. This is the first case of AA to show involvement of cardiac valves, indicating the importance of systematic examination for patients with AA and cardiac valve involvement.

• Authors: Shin Fukuda, Toshihiro Nanki, Tomohiro Morio, Hisanori Hasegawa, Ryuji Koike, Nobuyuki Miyasaka
• Journal: Modern rheumatology (Mod Rheumatol) Vol. 24 Issue 3 Pg. 537-9 (May 2014) ISSN: 1439-7609 [Electronic] England
• PMID: 24506570 (Publication Type: Case Reports, Journal Article)

Topics

• Abscess (complications, immunology)
• Female
• Humans
• Middle Aged
• Mitral Valve Insufficiency (complications, immunology)
• Neutrophil Infiltration (immunology)