Citriquinones A and B, new benzoquinones from Penicillium citrinum.

Abstract

Two new benzoquinones, citriquinone A (1) and B (2), were isolated from the methanol extract of a soil fungus, Penicillium citrinum. The structures of the new compounds were determined on the basis of detailed spectroscopic analysis. Citriquinone A (1) exhibited antibacterial activity against Bacillus sp. and cell migration inhibitory activity (CMIA) against human cancer cell line HEp 2.

• Authors: P K Vinitha Ranji, S Chandrani Wijeyaratne, K Hector Jayawardana, G M Kamal B Gunaherath
• Journal: Natural product communications (Nat Prod Commun) Vol. 8 Issue 10 Pg. 1431-4 (Oct 2013) ISSN: 1934-578X [Print] United States
• PMID: 24354194 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antineoplastic Agents
• Benzoquinones
• citriquinone A
• citriquinone B

Topics

• Antineoplastic Agents (chemistry, isolation & purification, pharmacology)
• Bacillus
• Benzoquinones (chemistry, isolation & purification, pharmacology)
• Cell Line, Tumor
• Cell Movement (drug effects)
• Drug Screening Assays, Antitumor
• Humans
• Microbial Sensitivity Tests
• Penicillium (chemistry)