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A case of midgut carcinoid with breast metastasis and cellular localization of serotonin and substance P.

Abstract
A case of midgut carcinoid with breast metastasis is reported. Hepatic metastases stored large amounts of serotonin as demonstrated by the Falck-Hillarp technique. Immunocytochemically serotonin and substance P, which may co-exist in gut enterochromaffin cells, were demonstrated in separate populations of tumor cells both in the hepatic and mammary neoplasms.
AuthorsH Ahlman, I Larsson, K Grönstad, L E Tisell, A Dahlström
JournalJournal of surgical oncology (J Surg Oncol) Vol. 31 Issue 3 Pg. 170-3 (Mar 1986) ISSN: 0022-4790 [Print] United States
PMID2425188 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Serotonin
  • Substance P
Topics
  • Aged
  • Breast (pathology)
  • Breast Neoplasms (analysis, secondary)
  • Carcinoid Tumor (analysis, pathology, secondary)
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Ileal Neoplasms (pathology)
  • Liver (pathology)
  • Liver Neoplasms (analysis)
  • Malignant Carcinoid Syndrome (metabolism)
  • Serotonin (analysis)
  • Substance P (analysis)

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