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The specific characteristics of DIC syndrome vary with different clinical settings in the newborn.

Abstract
Abstract Two hundred fourteen newborns with serious perinatal pathology (posthypoxic syndrome, sepsis, surgical intervention, etc.) were examined in progress, according to 27 parameters including coagulative, trombocitic, anti-coagulative and fibrinolitic parts of hemostasis system. It was proved, that neonatal disseminated intravascular coagulation (DIC) syndrome had different hemostasiological patterns, which were connected with the genesis: sepsis, surgical intervention or posthypoxic syndrome. Precise periods of DIC syndrome are not always presented in newborns. DIC syndrome with neonatal sepsis has two different patterns (overcompensated and decompensated). The manifestation of trombo-hemorrhagic disorders and their characteristics depend on the genesis of DIC syndrome (e.g. an infection process and hyperbilirubinemia can provide the appearance of hemorrhagic syndrome).
AuthorsDmitry Ivanov, Nicolai Shabalov, Yiri Petrenko, Nina Shabalova, N A Treskina
JournalThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (J Matern Fetal Neonatal Med) Vol. 27 Issue 11 Pg. 1088-92 (Jul 2014) ISSN: 1476-4954 [Electronic] England
PMID24087921 (Publication Type: Journal Article)
Topics
  • Digestive System Abnormalities (complications, diagnosis, epidemiology, surgery)
  • Disseminated Intravascular Coagulation (complications, congenital, diagnosis, physiopathology)
  • Hemostasis (physiology)
  • Humans
  • Hypoxia (complications, congenital, epidemiology, physiopathology)
  • Incidence
  • Infant, Newborn
  • Infant, Newborn, Diseases (diagnosis, epidemiology, physiopathology, surgery)
  • Pneumonia (complications, congenital, epidemiology, physiopathology)
  • Sepsis (complications, congenital, epidemiology, physiopathology)
  • Severity of Illness Index
  • Syndrome

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