Abstract | BACKGROUND:
Gout is a metabolic disease by deposition of uric acid crystals, which undertakes joint and soft tissue in both acute and chronic stages. Is a rare event the onset of a tumor in the site of the lesion. OBJECTIVE: To present a rare case of association between sarcoma and tophi. METHODS: 83 year old man who consulted for tumor in his left elbow about 40 years of evolution, which spontaneously started to hurt. With the presumptive diagnosis of tophi treated surgically. The lesion recurred after 60 days, reintervention and radiotherapy was performed for diagnosis of malignant mesenchymal tumor associated with tophi. At 10 months developed ipsilateral nodal metastases, died within 2 years of the initial consultation. RESULTS: The diagnosis of the first material resected was tophi. In the reintervention material was diagnosed mesenchymal spindle cell high grade neoplasm associated with tophi; immunohistochemistry revealed: vimentin + / +, MYO D1 - / - ASMA - / -, FVIII - / -, A1ATT - / -, CD68-/ -, S100-/ - with final diagnosis the undifferentiated high grade pleomorphic sarcoma. CONCLUSIONS:
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Authors | Susana Szlabi, Jorge O Flores, Ana L de Diller, Marta Cabrera |
Journal | Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
(Rev Fac Cien Med Univ Nac Cordoba)
Vol. 69
Issue 4
Pg. 224-7
( 2012)
ISSN: 1853-0605 [Electronic] Argentina |
Vernacular Title | Sarcoma pleomórfico indiferenciado de alto grado/ fibrohistiocitoma maligno asociado a tofo gotoso. presentación de un caso. |
PMID | 23751790
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Aged, 80 and over
- Elbow Joint
- Fatal Outcome
- Gout
(complications, pathology)
- Histiocytoma, Benign Fibrous
(complications, pathology)
- Humans
- Male
- Sarcoma
(complications, pathology)
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