Abstract | BACKGROUND:
Hyperprolactinemia is a common endocrine disorder that can be associated with significant morbidity. We conducted a systematic review and meta-analyses of outcomes of hyperprolactinemic patients, including microadenomas and macroadenomas, to provide evidence-based recommendations for practitioners. Through this review, we aimed to compare efficacy and adverse effects of medications, surgery and radiotherapy in the treatment of hyperprolactinemia. METHODS: We searched electronic databases, reviewed bibliographies of included articles, and contacted experts in the field. Eligible studies provided longitudinal follow-up of patients with hyperprolactinemia and evaluated outcomes of interest. We collected descriptive, quality and outcome data ( tumor growth, visual field defects, infertility, sexual dysfunction, amenorrhea/ oligomenorrhea and prolactin levels). RESULTS: CONCLUSION:
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Authors | Amy T Wang, Rebecca J Mullan, Melanie A Lane, Ahmad Hazem, Chaithra Prasad, Nicola W Gathaiya, M Mercè Fernández-Balsells, Amy Bagatto, Fernando Coto-Yglesias, Jantey Carey, Tarig A Elraiyah, Patricia J Erwin, Gunjan Y Gandhi, Victor M Montori, Mohammad Hassan Murad |
Journal | Systematic reviews
(Syst Rev)
Vol. 1
Pg. 33
(Jul 24 2012)
ISSN: 2046-4053 [Electronic] England |
PMID | 22828169
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Topics |
- Evidence-Based Medicine
- Humans
- Hyperprolactinemia
(therapy)
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