Abstract |
A sensitive fluorescence strategy based on T7 exonuclease-assisted target recycling amplification was developed for telomerase detection in cancer cells. The novel strategy improved the fluorescence signal and sensitivity compared with the previously reported methods.
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Authors | Hai-bo Wang, Shuang Wu, Xia Chu, Ru-Qin Yu |
Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Vol. 48
Issue 47
Pg. 5916-8
(Jun 14 2012)
ISSN: 1364-548X [Electronic] England |
PMID | 22558640
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Telomerase
- Exodeoxyribonucleases
- gene b exonuclease
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Topics |
- Biosensing Techniques
- Cell Line, Tumor
- Exodeoxyribonucleases
(metabolism)
- Humans
- Neoplasms
(enzymology)
- Spectrometry, Fluorescence
- Telomerase
(metabolism)
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