Abstract |
Degenerative changes were observed in liver of rats treated with single and repeated doses of fenarimol (250 mg/kg body weight x day). Regenerative changes i.e. increase in: DNA synthesis, hepatic DNA, mitotic activity and number of binuclear hepatocytes, were also noted.
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Authors | D Palut, J Kopeć-Szlezak |
Journal | Roczniki Panstwowego Zakladu Higieny
(Rocz Panstw Zakl Hig)
Vol. 41
Issue 5-6
Pg. 253-61
( 1990)
ISSN: 0035-7715 [Print] Poland |
PMID | 2101177
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Fungicides, Industrial
- Pyrimidines
- DNA
- fenarimol
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Topics |
- Animals
- Cell Count
(drug effects)
- DNA
(biosynthesis, drug effects)
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Fatty Liver
(chemically induced, metabolism, pathology)
- Fungicides, Industrial
(administration & dosage, toxicity)
- Liver
(drug effects, metabolism, pathology)
- Male
- Mitosis
(drug effects)
- Pyrimidines
(administration & dosage, toxicity)
- Rats
- Rats, Inbred Strains
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