Repetitive transcranial magnetic stimulation to hemispatial neglect in patients after stroke: an open-label pilot study.
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| Abstract | OBJECTIVE: To test whether multiple sessions of inhibitory low-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the left parietal area can improve hemispatial neglect after stroke. DESIGN: An open-label design. PATIENTS: Seven consecutive patients with hemispatial neglect after right hemispheric stroke were compared with 7 retrospectively recruited control patients. METHODS: Seven patients received a session of 1 Hz rTMS to the left parietal area immediately prior to occupational therapy for 10 days. Seven control patients received only behavioural therapy. RESULTS: Baseline values of the line bisection test and the Albert test were comparable in the two groups. The stimulation group showed a greater improvement in the line bisection test than did the control group. However, no differences were found between the two groups according to the Albert test. CONCLUSION: In this pilot study, low-frequency rTMS application to the non-affected left parietal area was found to be safe and to improve line bisection test, which suggests that non-invasive cortical stimulation has a potential role as an adjuvant strategy during cognitive rehabilitation training in patients with hemispatial neglect. A prospective randomized, sham-controlled study is required to determine the beneficial role of non-invasive cortical stimulation on hemispatial neglect.
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| Authors | Jong Youb Lim, Eun Kyoung Kang, Nam-Jong Paik |
| Journal | Journal of rehabilitation medicine (J Rehabil Med) Vol. 42 Issue 5 Pg. 447-52 (May 2010) ISSN: 1651-2081 [Electronic] Sweden |
| PMID | 20544155 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't) |
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