Successful radiation therapy for supratentorial primitive neuroectodermal tumor and epidermolysis bullosa simplex.

Abstract

Epidermolysis bullosa simplex (EBS) is a heritable skin disorder characterized by skin fragility and blistering. While its most severe variant, dystrophic epidermolysis bullosa (DEB) is associated with squamous cell carcinoma (SCC), the development of extracutaneous neoplasms in EBS is extremely rare. We report a novel case of supratentorial primitive neuroectodermal tumor (sPNET) in a 7-year male with EBS. Experience of radiation therapy and its challenges in children with EBS has rarely been reported.

• Authors: Sejal Bavishi, Kenneth Wong, Thamani Delgardo, Araz Marachelian, Soumen Khatua
• Journal: Pediatric blood & cancer (Pediatr Blood Cancer) Vol. 54 Issue 1 Pg. 170-2 (Jan 2010) ISSN: 1545-5017 [Electronic] United States
• PMID: 19760773 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2009 Wiley-Liss, Inc.

Topics

• Carcinoma, Squamous Cell (pathology, radiotherapy)
• Child
• Epidermolysis Bullosa Simplex (pathology, radiotherapy)
• Feasibility Studies
• Humans
• Magnetic Resonance Imaging
• Male
• Neuroectodermal Tumors, Primitive (pathology, radiotherapy)
• Skin Neoplasms (pathology, radiotherapy)