Abstract | OBJECTIVE: METHODS: RESULTS: WT1 positivity was noticed in tumor cells and endothelial cells, lining the intratumoral blood vessels. Overall, 72% (26/36) of tumors stained positive for WT1. RT-PCR results showed WT1 positivity in 75% (24/32) of samples. Comparing the staining patterns of the 3 different bioptic sites, tumor heterogeneity was demonstrated in the majority (72%) of samples. CONCLUSION:
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Authors | An Coosemans, Philippe Moerman, Godelieve Verbist, Wim Maes, Patrick Neven, Ignace Vergote, Stefaan W Van Gool, Frédéric Amant |
Journal | Gynecologic oncology
(Gynecol Oncol)
Vol. 111
Issue 3
Pg. 502-8
(Dec 2008)
ISSN: 1095-6859 [Electronic] United States |
PMID | 18929401
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adenocarcinoma, Clear Cell
(genetics, metabolism, pathology)
- Aged
- Biopsy
- Carcinoma, Endometrioid
(genetics, metabolism, pathology)
- Cystadenocarcinoma, Serous
(genetics, metabolism, pathology)
- Endometrial Neoplasms
(genetics, metabolism, pathology)
- Female
- Genes, Wilms Tumor
- Humans
- Immunohistochemistry
- Neoplasm Staging
- Reverse Transcriptase Polymerase Chain Reaction
- WT1 Proteins
(biosynthesis, genetics)
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