The efficacy of Lasix-vitamin therapy (L-V therapy) for sudden deafness and other sensorineural hearing loss.

Abstract

The efficacy of Lasix-vitamin therapy (L-V therapy) for sudden deafness (SD) was compared with that of conventional therapeutic regimens. There was no significant difference in efficacy between the two therapies. However, in fresh cases (within 7 days from onset of SD), L-V therapy gave a cure rate of 42.3% and an effectiveness rate of 88.4%, these rates being higher than those obtained with conventional therapy; and in cases treated within 4 weeks, L-V therapy was significantly more effective than conventional therapy. Besides, in cases with severe hearing loss (more than 70 dB hearing level) or vestibular symptoms, which were important factors of prognosis, L-V therapy proved more efficient. The efficacy of L-V therapy for other sensorineural hearing loss was also evaluated. In Meniere's disease, L-V therapy proved effective in 45.9% of cases, but with only a 20-30% effectiveness rate in other cases, e.g. idiopathic hearing loss, head and neck injury, noise-induced hearing loss and chronic otitis media.

• Authors: K Konishi, Y Nakai, H Yamane
• Journal: Acta oto-laryngologica. Supplementum (Acta Otolaryngol Suppl) Vol. 486 Pg. 78-91 ( 1991) ISSN: 0365-5237 [Print] Norway
• PMID: 1842883 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Drug Combinations
• Vitamins
• Furosemide

Topics

• Adult
• Aged
• Drug Combinations
• Female
• Furosemide (administration & dosage, therapeutic use)
• Hearing Loss, Sensorineural (drug therapy, epidemiology)
• Hearing Loss, Sudden (drug therapy, epidemiology)
• Humans
• Male
• Meniere Disease (drug therapy, epidemiology)
• Middle Aged
• Retrospective Studies
• Vitamins (administration & dosage, therapeutic use)