Diagnosis and treatment of Gardner syndrome with gastric polyposis: a case report and review of the literature.

Abstract

Gardner syndrome (GS) is an autosomal dominant disease characterized by the presence of colonic polyposis, osteoma and soft tissue tumors. It is regarded as a clinical subgroup of familial adenomatous polyposis (FAP) and may present at any age from 2 mo to 70 years with a variety of symptoms, either colonic or extracolonic. We present a case of a 23-year-old female patient with GS who presented with gastric polyposis and was successively treated with restorative proctocolectomy in combination with ileal pouch anal anastomosis (RPC/ IPAA), ileostomy, ileostomy closure operation, snare polypectomy during 8 mo. After operation, the patient took oral traditional Chinese medicine pills made of Fructus mume and Bombyx batryticatu for about 6 mo. The innutrition and anaemia of this patient were gradually improved. Gastroscopy showed that the remnant gastric polypi gradually decreased and finally disappeared 19 mo after the first operation. The patient had 2-3 times of solid stool per day at the time we wrote this paper.

• Authors: Guo-Li Gu, Shi-Lin Wang, Xue-Ming Wei, Li Bai
• Journal: World journal of gastroenterology (World J Gastroenterol) Vol. 14 Issue 13 Pg. 2121-3 (Apr 07 2008) ISSN: 1007-9327 [Print] United States
• PMID: 18395919 (Publication Type: Case Reports, Journal Article)

Chemical References

• Plant Extracts

Topics

• Adult
• Animals
• Bombyx (metabolism)
• Endoscopy
• Female
• Gardner Syndrome (complications, diagnosis, therapy)
• Humans
• Medicine, Chinese Traditional
• Plant Extracts (therapeutic use)
• Polyps (complications, diagnosis, therapy)
• Proctocolectomy, Restorative (methods)
• Stomach Diseases (complications, diagnosis, therapy)
• Time Factors
• Treatment Outcome