Abstract | TOPIC: CLINICAL RELEVANCE: METHODS/LITERATURE REVIEWED: English and non-English articles were retrieved using a keyword search of Medline (1966 onwards), Embase, the Cochrane Collaboration, the National Institute of Health Clinical Trials Database, and the Association for Research in Vision and Ophthalmology Annual Meeting Abstract Database (2003-2005). This was supplemented by hand searching references of review articles. Two investigators independently identified all randomized clinical trials (RCTs) with more than 3 months' follow-up. RESULTS: CONCLUSIONS: There is limited level I evidence for any interventions for BRVO. The BVOS showed that macular grid laser photocoagulation is an effective treatment for macular edema and improves vision in eyes with VA of 20/40 to 20/200, and that scatter laser photocoagulation can effectively treat neovascularization. The effectiveness of many new treatments is unsupported by current evidence.
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Authors | Rachel L McIntosh, Quresh Mohamed, Seang Mei Saw, Tien Yin Wong |
Journal | Ophthalmology
(Ophthalmology)
Vol. 114
Issue 5
Pg. 835-54
(May 2007)
ISSN: 1549-4713 [Electronic] United States |
PMID | 17397923
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review, Systematic Review)
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Chemical References |
- Angiogenesis Inhibitors
- Glucocorticoids
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Topics |
- Angiogenesis Inhibitors
(therapeutic use)
- Evidence-Based Medicine
- Glucocorticoids
(therapeutic use)
- Hemodilution
(methods)
- Humans
- Laser Coagulation
(methods)
- Macular Edema
(prevention & control)
- Ophthalmologic Surgical Procedures
- Randomized Controlled Trials as Topic
- Retinal Neovascularization
(prevention & control)
- Retinal Vein Occlusion
(therapy)
- Visual Acuity
- Vitrectomy
- Vitreous Hemorrhage
(prevention & control)
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