Treatment of Dientamoeba fragilis infection with paromomycin.

Abstract

Treatment with paromomycin (25-35 mg/kg/d for 7 days) was evaluated prospectively in 15 children with Dientamoeba fragilis infection after 1-month follow-up. At the end of the study, parasitologic effectiveness and clinical improvement were observed in 12/15 (80%) and 13/15 (87%) patients, respectively. Paromomycin appears to be an effective drug for treatment of D. fragilis infection in children.

• Authors: Olivier Vandenberg, Hichem Souayah, Françoise Mouchet, Anne Dediste, Tom van Gool
• Journal: The Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 26 Issue 1 Pg. 88-90 (Jan 2007) ISSN: 0891-3668 [Print] United States
• PMID: 17195717 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Amebicides
• Paromomycin

Topics

• Adolescent
• Amebicides (therapeutic use)
• Animals
• Child
• Child, Preschool
• Dientamoeba (isolation & purification)
• Dientamoebiasis (drug therapy)
• Female
• Gastrointestinal Diseases (drug therapy, parasitology)
• Humans
• Infant
• Male
• Paromomycin (therapeutic use)