The effects of neuromuscular alterations in elders with cancer.

Abstract

OBJECTIVES:

To review the effects of normal aging on declines in function of peripheral nerves and muscles and the additive effects of chemotherapy and comorbidity in elders undergoing cancer treatment.

DATA SOURCES:

Research studies and published articles.

CONCLUSION:

Chemotherapy negatively affects physical functioning and recovery in elders with cancer through neurotoxicity and myotoxicity. Intact sensory nerves and muscles are crucial in maintaining physical function and independence for elders.

IMPLICATIONS FOR NURSING PRACTICE:

While older patients with cancer may benefit from chemotherapy, clinical practices to minimize toxicities, provide monitoring for functional decline, and intervene to maintain function are needed.

• Authors: Constance Visovsky
• Journal: Seminars in oncology nursing (Semin Oncol Nurs) Vol. 22 Issue 1 Pg. 36-42 (Feb 2006) ISSN: 0749-2081 [Print] United States
• PMID: 16458181 (Publication Type: Journal Article, Review)

Chemical References

• Antineoplastic Agents

Topics

• Age Factors
• Aged
• Aging (drug effects, physiology)
• Antineoplastic Agents (adverse effects)
• Comorbidity
• Geriatric Assessment
• Health Services Needs and Demand
• Humans
• Mass Screening
• Muscle Weakness (diagnosis, etiology, prevention & control)
• Muscle, Skeletal (drug effects, physiology)
• Neoplasms (complications, drug therapy)
• Neurologic Examination
• Neurotoxicity Syndromes (diagnosis, etiology, prevention & control)
• Nursing Assessment
• Nursing Research
• Oncology Nursing
• Peripheral Nerves (drug effects, physiology)
• Risk Factors