In vitro activities of moxifloxacin against 900 aerobic and anaerobic surgical isolates from patients with intra-abdominal and diabetic foot infections.

Abstract	The in vitro activities of moxifloxacin, ciprofloxacin, levofloxacin, gatifloxacin, imipenem, piperacillin-tazobactam, clindamycin, and metronidazole against 900 surgical isolates were determined using NCCLS testing methods. Moxifloxacin exhibited good to excellent antimicrobial activity against most aerobic (90.8%) and anaerobic (97.1%) microorganisms, suggesting that it may be effective for the treatment of polymicrobial surgical infections.
Authors	Charles E Edmiston, Candace J Krepel, Gary R Seabrook, Lewis R Somberg, Atilla Nakeeb, Robert A Cambria, Jonathan B Towne
Journal	Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 48 Issue 3 Pg. 1012-6 (Mar 2004) ISSN: 0066-4804 [Print] United States
PMID	14982797 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Anti-Infective Agents Aza Compounds Fluoroquinolones Quinolines Moxifloxacin
Topics	Abdomen (microbiology) Anti-Infective Agents (pharmacology) Aza Compounds (pharmacology) Bacteria, Aerobic (drug effects) Bacteria, Anaerobic (drug effects) Bacterial Infections (microbiology) Diabetic Foot (microbiology, surgery) Fluoroquinolones Humans Microbial Sensitivity Tests Moxifloxacin Quinolines (pharmacology)

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